Oleg V Evgenov Selected Research

3- (4- Amino- 5- cyclopropylpyrimidine- 2- yl)- 1- (2- fluorobenzyl)- 1H- pyrazolo(3,4- b)pyridine

1/2013	Soluble guanylate cyclase stimulators in pulmonary hypertension.
12/2007	Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation.
10/2004	Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs.

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Oleg V Evgenov Research Topics

Disease

8	Pulmonary Hypertension 01/2013 - 12/2002
4	Lung Injury 03/2004 - 12/2002
2	Left Ventricular Dysfunction 01/2013 - 03/2010
2	Fibrosis (Cirrhosis) 01/2013 - 03/2010
2	Inflammation (Inflammations) 03/2010 - 10/2009
2	Hemorrhagic Shock 07/2005 - 10/2003
1	Cardiomegaly (Heart Hypertrophy) 01/2013
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2013
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2013
1	Heart Failure 01/2013
1	Malignant Hypertension 01/2011
1	Hypertension (High Blood Pressure) 01/2011
1	Cardiovascular Diseases (Cardiovascular Disease) 03/2010
1	Cardiomyopathies (Cardiomyopathy) 03/2010
1	Atherosclerosis 10/2009
1	Vascular Remodeling 10/2009
1	Infections 06/2008
1	Cystic Fibrosis (Mucoviscidosis) 06/2008
1	Shock 07/2005
1	Bradycardia 03/2004
1	Cardiac Edema 03/2004
1	Hypoxia (Hypoxemia) 03/2004
1	Hemorrhage 10/2003
1	Septic Shock (Toxic Shock Syndrome) 05/2003
1	Sepsis (Septicemia) 02/2003
1	Pneumonia (Pneumonitis) 02/2003
1	Acute Lung Injury 01/2003
1	Endotoxemia 01/2003
1	Edema (Dropsy) 12/2002

Drug/Important Bio-Agent (IBA)

5	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2011 - 12/2002
3	3- (4- Amino- 5- cyclopropylpyrimidine- 2- yl)- 1- (2- fluorobenzyl)- 1H- pyrazolo(3,4- b)pyridineIBA 01/2013 - 10/2004
3	Soluble Guanylyl CyclaseIBA 01/2013 - 10/2004
3	Oxygen (Dioxygen)IBA 03/2010 - 02/2003
3	EndotoxinsIBA 03/2004 - 12/2002
2	BAY 41-8543IBA 01/2013 - 12/2007
2	riociguatIBA 01/2013 - 01/2011
2	NitrogenIBA 03/2010 - 07/2005
2	Vasodilator Agents (Vasodilators)IBA 04/2006 - 10/2004
2	LipopolysaccharidesIBA 03/2004 - 02/2003
2	Pharmaceutical PreparationsIBA 10/2003 - 05/2003
2	Methylene Blue (Methylthioninium Chloride)FDA Link 05/2003 - 01/2003
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2010
1	AntioxidantsIBA 03/2010
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 03/2010
1	p38 Mitogen-Activated Protein KinasesIBA 03/2010
1	EndocannabinoidsIBA 03/2010
1	Thromboplastin (Tissue Factor)IBA 10/2009
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2008
1	PowdersIBA 12/2007
1	vinpocetineIBA 04/2006
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 04/2006
1	IsoenzymesIBA 04/2006
1	Poly (ADP-Ribose) Polymerase-1IBA 07/2005
1	Peroxynitrous Acid (Peroxynitrite)IBA 07/2005
1	Endothelin-1 (Endothelin 1)IBA 03/2004
1	tezosentanIBA 03/2004
1	Endothelin Receptor AntagonistsIBA 03/2004
1	SaltsIBA 10/2003
1	Blood Glucose (Blood Sugar)IBA 10/2003
1	SodiumIBA 10/2003
1	Potassium Channels (Potassium Channel)IBA 10/2003
1	Adenosine Triphosphate (ATP)IBA 10/2003
1	KATP ChannelsIBA 10/2003
1	Glipizide (Glucotrol)FDA LinkGeneric 10/2003
1	Toll-Like Receptor 5IBA 02/2003
1	FlagellinIBA 02/2003
1	PolyethyleneimineIBA 12/2002

Therapy/Procedure

1	Therapeutics 01/2013
1	Injections 10/2003
1	Intravenous Administration 02/2003